Fasting state: some lab tests require fasting; others do not. Lipids on a fasting draw differ from lipids on a fed draw. Always note whether the test was fasting when comparing results.
Revisiting: How to bring a laboratory report to an appointment usefully posts 151–155
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.
I read post #151 twice before replying, because I had assumed the opposite.
TSH and free hormones: TSH is a reasonable screening test but does not tell you about actual free hormone levels. If TSH is abnormal, free thyroid hormones confirm whether there is a real thyroid problem.
Reference intervals: constructed to contain the central 95% of a reference population, which means one in twenty healthy people falls outside one by definition. Add biological variation and analytical imprecision and the base rate of a meaningless flag is substantial.
Time of day: some biomarkers vary across the day. Cortisol in the morning differs from cortisol in the evening. Comparing results from different times of day is comparing things that are not the same.
Suggested topics
| Topic | Participants | Replies | Views | Activity |
|---|---|---|---|---|
|
Lipase elevation without symptoms: the interpretation problem
Lipase elevation without symptoms: the interpretation problem Writing it up because I had to work it out twice and would rather nobody else did. Asking about a population rather than about a person. The…
|
+21 | 25 | 62k | 5mo |
|
How to bring a laboratory report to an appointment usefully
How to bring a laboratory report to an appointment usefully — that is the question, and I have not found it answered plainly anywhere I have looked. General question, not a request for advice about my own…
|
2 | 41k | 14mo | |
|
Revisiting: Liver enzymes drifting down and what that usually means
On the subject in the title: Revisiting: Liver enzymes drifting down and what that usually means Working notes rather than a conclusion. General question, not a request for advice about my own care — I know…
|
+55 | 61 | 39k | 3h |
|
HbA1c lag and what it can and cannot tell you at eight weeks — one year on
Posting this under the heading it deserves: HbA1c lag and what it can and cannot tell you at eight weeks — one year on Everything below is what sits behind that. General question, not a request for advice…
|
+18 | 22 | 655 | 13h |
|
eGFR fluctuation and the creatinine denominator problem — the long version
eGFR fluctuation and the creatinine denominator problem — the long version — setting out what I have, and where I think it stops being reliable. Asking about a population rather than about a person. The…
|
+43 | 47 | 17k | just now |
Related topics — sharing the tags HbA1c, liver enzymes, eGFR & renal function
| Topic | Participants | Replies | Views | Activity |
|---|---|---|---|---|
|
Fasting versus non-fasting and which tests care
Fasting versus non-fasting and which tests care Writing it up because I had to work it out twice and would rather nobody else did. General question, not a request for advice about my own care — I know the…
|
+72 | 78 | 14k | 19h |
|
Biological variation versus analytical imprecision — does this still hold?
The question in the title: Biological variation versus analytical imprecision — does this still hold? I will give what I have already checked below so nobody repeats it. Asking about a population rather than…
|
2 | 1.8k | 8mo | |
|
Micronutrient status when intake falls substantially — a second dataset
Micronutrient status when intake falls substantially — a second dataset Writing it up because I had to work it out twice and would rather nobody else did. Asking about a population rather than about a person.…
|
+9 | 13 | 274 | 14mo |
|
Lipase elevation without symptoms: the interpretation problem
Lipase elevation without symptoms: the interpretation problem Writing it up because I had to work it out twice and would rather nobody else did. Asking about a population rather than about a person. The…
|
+21 | 25 | 62k | 5mo |
|
Which panel is worth repeating and which is worth ignoring — a second dataset
Asking directly, because I could not find a straight answer: Which panel is worth repeating and which is worth ignoring — a second dataset General question, not a request for advice about my own care — I know…
|
+108 | 117 | 46k | 4mo |