Tags · Practice
sterile water
Preservative-free water for injection.
Related in this group: reconstitution · bacteriostatic water · concentration maths · syringe units · dead volume · titration · dose reduction · missed dose · injection site rotation · needle gauge & length · subcutaneous injection · storage
15 topics
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Coming back to: Solubility limits and what a cloudy solution is telling you
On the subject in the title: Solubility limits and what a cloudy solution is telling you Working notes rather than a conclusion. Reading back through what has been written here about Solubility limits, three…
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+38 | 43 | 29k | 13h |
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Preservatives: function, testing, and limits — one year on
On the subject in the title: Preservatives: function, testing, and limits — one year on Working notes rather than a conclusion. Asking about Preservatives directly, because I have read four threads on it and…
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+28 | 32 | 437 | 8d |
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Follow-up: Lyophilisation and why the cake looks the way it does
Lyophilisation and why the cake looks the way it does Writing it up because I had to work it out twice and would rather nobody else did. I was wrong about Lyophilisation in a thread last spring and I would…
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+10 | 14 | 11k | 3mo |
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[2026 update] Buffers, pH and why a formulation is a formulation
Posting this under the heading it deserves: Buffers, pH and why a formulation is a formulation Everything below is what sits behind that. A formulation question rather than a pharmacological one, though the…
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2 | 773 | 3mo | |
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Adsorption to container surfaces and to plastics
On the subject in the title: Adsorption to container surfaces and to plastics Working notes rather than a conclusion. I was wrong about adsorption in a thread last spring and I would like to correct it…
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+13 | 17 | 4.3k | 5mo |
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Lyophilisation and why the cake looks the way it does
Posting this under the heading it deserves: Lyophilisation and why the cake looks the way it does Everything below is what sits behind that. I was wrong about lyophilisation in a thread last spring and I…
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+33 | 37 | 60k | 6mo |
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Second pass at: Isotonicity and what happens when you get it wrong
Second pass at: Isotonicity and what happens when you get it wrong — setting out what I have, and where I think it stops being reliable. Something about Isotonicity does not reconcile and I would like a…
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+1 | 5 | 2.6k | 11mo |
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Excipient function in a licensed injectable
Excipient function in a licensed injectable Writing it up because I had to work it out twice and would rather nobody else did. I was wrong about excipient function in a thread last spring and I would like to…
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+3 | 7 | 36k | 14mo |
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Excipient function in a licensed injectable — the long version
Posting this under the heading it deserves: Excipient function in a licensed injectable — the long version Everything below is what sits behind that. A narrow question about Excipient function, deliberately…
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2 | 100 | 15mo | |
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Preservatives: function, testing, and limits
Preservatives: function, testing, and limits — setting out what I have, and where I think it stops being reliable. An honest uncertainty about preservatives rather than a disguised assertion. I do not know…
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+23 | 27 | 3.7k | 16mo |
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Coming back to: Adsorption to container surfaces and to plastics
Adsorption to container surfaces and to plastics — setting out what I have, and where I think it stops being reliable. Adsorption — I have the observation and I do not trust my interpretation of it, so I am…
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2 | 459 | 17mo | |
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About the Formulation chemistry category
Buffers, pH, isotonicity, preservatives, lyophilisation and excipient function. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author and…
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4 | 4.5k | 18mo | |
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Isotonicity and what happens when you get it wrong
On the subject in the title: Isotonicity and what happens when you get it wrong Working notes rather than a conclusion. I was wrong about isotonicity in a thread last spring and I would like to correct it…
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+27 | 31 | 11k | 18mo |
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Buffers, pH and why a formulation is a formulation
Buffers, pH and why a formulation is a formulation Writing it up because I had to work it out twice and would rather nobody else did. A formulation question rather than a pharmacological one, though the two…
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+11 | 15 | 51k | 21mo |
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Second pass at: Buffers, pH and why a formulation is a formulation
Second pass at: Buffers, pH and why a formulation is a formulation Writing it up because I had to work it out twice and would rather nobody else did. Posting a small dataset on Buffers. It is mine, it is…
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+24 | 28 | 1.5k | 21mo |