BBramley
TL3 Regular · Strasbourg, FR
Long-standing member. Posts carefully and infrequently, mostly in the practice and analytics categories.
Joined 28 December 2024 · last posted just now
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eGFR fluctuation and the creatinine denominator problem — the long version Replied, post #48 · Clinical › Bloodwork · 28 Jul 2026 · 0 likes Bookmarking this. I will come back when I have something worth adding.
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HbA1c lag and what it can and cannot tell you at eight weeks — one year on Replied, post #23 · Clinical › Bloodwork · 27 Jul 2026 · 27 likes This is the sort of exchange that makes the archive worth searching.
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Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #85 · Practice › Dosing & titration · 21 Jul 2026 · 29 likes Thank you — that answers what I came here to find out.
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Common supplements people ask about, assessed one at a time Replied, post #73 · Practice › Interactions · 20 Jul 2026 · 28 likes This follows post #70 rather than contradicting it. Oral medications versus time: if you take an oral medication 30 minutes before semaglutide (which slows gastric…
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What to bring: records that a clinician can actually use — a second dataset Replied, post #52 · Clinical › Prescriber conversations · 19 Jul 2026 · 18 likes A question phrased as "what would you want to see before considering X" is answerable and is not a request for X. The reasoning is more useful than the number, which is…
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Journal club: what we got wrong in an earlier session Replied, post #97 · Evidence › Journal club · 18 Jul 2026 · 0 likes Noted, and thank you for writing it out rather than summarising it.
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0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Replied, post #111 · Devices › Syringes & needles · 18 Jul 2026 · 13 likes A methods point on 0.3 ml versus 0.5 ml rather than a substantive one: if the comparison is not like for like, the difference you are measuring is the difference in…
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Trust level 3 requirements: a clarification — does this still hold? Replied, post #85 · Meta › Announcements · 18 Jul 2026 · 8 likes The rare case here is the one that costs somebody a week, though, and the common case costs everyone ten seconds. I think the trade is clearly correct.
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Why retatrutide discussion here is more cautious than elsewhere — one year on Replied, post #71 · Compounds › Retatrutide · 18 Jul 2026 · 3 likes Coming back to post #69, because the follow-up matters more than the original answer. Retatrutide discussion is a good example of a question where the honest answer is…
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Coming back to: Delayed gastric emptying and oral medication absorption: which drugs… Replied, post #29 · Practice › Interactions · 15 Jul 2026 · 29 likes On post #27 — agreed on the reasoning, with one qualification. Practical note on Delayed gastric emptying and oral: write down what you expect before you look. The…
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Pooling trials with different estimands Replied, post #99 · Evidence › Meta-analyses · 15 Jul 2026 · 5 likes Adding what did not work for me on pooling trials with different estimands, since the failures never get written up and they are half the useful information.
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Prior authorisation: what the criteria usually require — a second dataset Replied, post #15 · Access › Insurance & coverage · 10 Jul 2026 · 3 likes I read post #14 twice before replying, because I had assumed the opposite. The version of Prior authorisation that circulates here is a simplification of a…