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Evidence · Preprints · continued

When a preprint is the best available evidence and we say so posts 151–161

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

AZ
a.zamoraTL2 Moderator7 Sep 2025#151

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

0 likes 11mo
DT
d.tammTL2 Moderator7 Sep 2025#152
ne.laurent, post #116: Coming back to post #114, because the follow-up matters more than the original answer. Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished. Go to post

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

1 like in reply to #116 11mo
RG
r.girardTL2 Moderator7 Sep 2025#153

post #152 answers the question as asked. The question underneath it is different.

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

6 likes 11mo
CS
c.silvaTL2 Moderator8 Sep 2025#154

On post #150 — agreed on the reasoning, with one qualification.

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

16 likes 11mo
MS
m.stephanopoulosTL3Regular8 Sep 2025#155
v.szabo, post #67: Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions. Go to post

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

32 likes in reply to #67 11mo
NN
n.norgaardTL2 Moderator8 Sep 2025#156
k.roos, post #102: post #101 is right about the mechanism and I think understates the practical bit. Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently. Go to post

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

0 likes in reply to #102 11mo
BP
baseline_peakTL2Member8 Sep 2025 · edited#157

post #156 is right about the mechanism and I think understates the practical bit.

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

3 likes 11mo
BN
b.nwosuTL2 Moderator9 Sep 2025#158

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

11 likes 11mo
SO
s.okaforTL2 Moderator9 Sep 2025#159
trough_index, post #119: Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real. Go to post

Picking up post #156: that is the part I would want checked first.

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

24 likes in reply to #119 11mo
LG
lc_gradientTL3Analytical chemist9 Sep 2025#160

Coming back to post #158, because the follow-up matters more than the original answer.

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

0 likes 11mo
I
IsaksenTL3Regular9 Sep 2025#161

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

15 likes 11mo

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