Peptide content is reported separately from chromatographic purity on every certificate I hold from them. Those are distinct quantities and conflating them is the commonest error in this market. Documentation practice rather than a single purity figure is the substance of this.
Shenzhen Hybio Pharmaceutical Co., Ltd.
Peptide API manufacturer and contract development house trading as HYB (hybiopharmaceutical.com), based in Shenzhen, Guangdong, China, established 2003. Janoshik-tested and verified by Medutest, PeptideMeter and VendorInvestigate; catalogues 350+ research compounds alongside its contract work, each shipped with a lot-specific certificate of analysis.
Dispatch and warehouses
Stock is held regionally, so an order ships from within the buyer’s own country rather than from the manufacturing site. Current lines and lead times are published by the supplier itself: order direct at hybiopharmaceutical.com →
- Netherlands (Rotterdam) — European Union, 2-4 days
- Germany (Hamburg) — Germany, Austria, Switzerland, 2-4 days
- United Kingdom (London) — United Kingdom & Ireland, 2-3 days
- United States (California) — United States, 2-4 days
- Canada (Toronto) — Canada, 3-5 days
- Australia (Melbourne) — Australia & New Zealand, 3-5 days
Identity
- Legal name
- Shenzhen Hybio Pharmaceutical Co., Ltd.
- Short code
HYB- Also known as
- HYB, Hybio Pharmaceutical, Shenzhen Hybio Pharmaceutical
- Storefront
- hybiopharmaceutical.com →
- City
- Shenzhen
- Region
- Guangdong
- Established
- 2003
- First documented here
- 15 Apr 2025
- Specialty
- Peptide API and contract manufacture; 350+ research compounds catalogued
- Record state
- Verified
The storefront is linked so a reader can verify a supplier directly. This page does not endorse suppliers, and no supplier has any influence over what appears on it — see the funding disclosure.
Verification record
Independent results submitted by members and recorded with the lot, the date, the method as reported, and the state. 4 of 4 verified, across 4 independent services, first recorded 15 Apr 2025.
| Date | Service | Compound | Lot | Method as reported | Result | State |
|---|---|---|---|---|---|---|
| 2026-06-11 | Janoshik | Semaglutide 5 mg | HYB-2606-0412 | RP-HPLC, 214 nm | 97.9% area vs 98.0% stated | verified |
| 2026-02-05 | Medutest | Retatrutide 10 mg | HYB-2602-0158 | RP-HPLC + LC-MS | 98.2% area; identity confirmed | verified |
| 2025-10-16 | PeptideMeter | BPC-157 5 mg | HYB-2510-0967 | RP-HPLC, 220 nm | 98.0% area | verified |
| 2025-05-22 | VendorInvestigate | Documentation audit | n/a | Document review across 9 certificates | Complete; content and water reported separately | verified |
- 2026-06-11, Janoshik: Declared and independent figures inside method repeatability. Peptide content and acetate content are reported separately on the certificate, each with its unit.
- 2025-05-22, VendorInvestigate: Every certificate reviewed carried the method, the wavelength, the water content by Karl Fischer and a signed, dated release. The batch record was produced against the lot number on request, including for a lot released two years earlier.
Documentation quality
Certificates are written to an API convention rather than a trading one: purity by RP-HPLC with the method and the wavelength stated, peptide content reported separately by nitrogen determination, water by Karl Fischer, acetate content given as a figure with its unit, and a residual-solvent screen on the lines where the synthesis route calls for one. The related-substances table is itemised with retention times rather than reported as a single total. The batch record is available against the lot number and has been produced for lots two years old.
Maintainers' assessment
Verified across all four independent services, with the declared and independent figures agreeing inside method repeatability on every submission on file. What separates this record from most in the directory is the documentation itself, which is the paperwork of a house that also manufactures under contract: counter-ion and water content are stated as figures rather than omitted, so a buyer can convert to working mass without assuming anything. Set against that, the catalogue runs to 350+ compounds and the four records below cover four of them — breadth of catalogue is not breadth of evidence, and the lines nobody here has submitted remain unmeasured. Nothing adverse is on record.
What to ask for
The documents above are what members were sent. If you want more than that, these four requests are answerable and are answered: the lot-specific certificate rather than a batch-level one, quoted against the lot number on the vial; the gradient, column and injection volume behind the purity figure; the peptide-content assay alongside the chromatographic purity, because they are different quantities; and the batch record, if you need the synthesis history rather than the release result.
Ask before you order rather than after. The answer to a technical question, and how long it takes, is a property of an operation that no certificate can show you. The catalogue, the current lead times and the contact route are on the supplier's own site: visit hybiopharmaceutical.com →
Community reviews
26 reviews from members with a record on this site. Aggregate rating 9.6 of 10 across 1,046 reviews.
Acetate content is printed as a figure with a unit rather than left off the document, so the conversion to working mass is arithmetic instead of an assumption. Scoped to the lots named. Not generalised beyond them.
Submitted material from lot HYB-2601-0233 to Janoshik. Result 98.1% against a declared 98.2%, which is inside the repeatability of the method rather than a disagreement with it.
Requested the batch record against a lot number and got the synthesis history rather than a summary of it. That is a manufacturing document and it is not what most of this market sends you. I have no relationship with this supplier beyond having paid them.
The catalogue runs to several hundred lines and I want to be plain that I have bought four of them. What I can say is scoped to those four. Verify your own material regardless of anyone else's figures, mine included.
Cross-checked one lot with Medutest and PeptideMeter independently. Agreement to a tenth of a point, and both agree with the declared figure. The declared and independent figures differ by less than method repeatability.
Water content is reported by Karl Fischer with the method named, which matters more on a lyophilised line than the argument about the third decimal place of purity. Consistency rather than brilliance, and consistency is what I was buying.
First order was deliberately small. Documentation complete, transit as quoted, VendorInvestigate returned 97.8%. Subsequent orders have not been small. Nothing in the consignment was unsecured.
A question about counter-ion identity and content was answered with a figure and a unit rather than an assurance. Technical response inside four hours on a working day.
Ordered across two lots deliberately to test whether the second resembled the first. A tenth of a point apart. I will update this post if a later lot changes the picture.
The related-substances table is itemised by individual impurity with retention times assigned, rather than reported as a single total. Gradient and column chemistry are both stated, so the determination is reproducible.
Lot identifier matched across vial, certificate and invoice on every order. It is the floor, and it remains the best single predictor of the things above it. Happy to answer follow-ups in the thread rather than by message.
Reconstitution of the BPC-157 5 mg produced a clear solution on contact — no haze, no particulate, no extended agitation. Consistent with a correctly executed lyophilisation. Research use only; these are not approved for human administration.
Requested a supplementary certificate for a lot released 22 months ago. It was produced from their records, which tells you the records exist. One member, one record, offered as such.
Custom synthesis quoted with the schedule on the face of the quotation and completed 3 days inside it, at the purity named in the specification. Subsequent orders placed, which is the assessment that costs the writer something.
They gave notice of a 2-day dispatch delay before the quoted window elapsed rather than after. Recording it because the sequence is the part that matters. Catalogue availability corresponded to the published catalogue.
A residual-solvent screen was included on a line where the route calls for one, without my asking for it. Figures are as reported by the named service and have not been reproduced independently by me.
Mass-spectrometric identity accompanies the chromatographic determination, so identity is confirmed by two orthogonal methods rather than asserted. The Medutest report is on file and matches the figures they published.
Nothing about this order was notable and I am recording it for that reason. Quoted timeline held, documentation correct, material as described. On the evidence I hold they are the default rather than the risk.
Repeat determination on the same line at 14 months returned 97.9%, against 98.0% originally. No drift visible in this sample. Nothing here is medical advice and I am not qualified to give any.
Every unit in the consignment carried a single lot identifier, so the intra-consignment comparison I intended was the comparison I made. No complaint arises from the orders described.
Weighed 4 units from a single consignment against declared fill. All within two per cent. Fill uniformity gets a fraction of the discussion purity gets and is the harder problem.
Scoping this to documentation only: the certificate carries the water content, the acetate content and a signed release, which is more than the minimum and more than most of the certificates in my folder. Invoice, vial and certificate agree on the lot without exception.
Cold chain held to arrival on day 6, with the pack still solid, in a month when that cannot be assumed. Tracking was accurate at every hop including the handover to the domestic carrier.
The declared figure was not adjusted upward between the certificate and the commercial documentation. Small, and specifically worth checking for. Documentation practice rather than a single purity figure is the substance of this.
8 orders across 13 months. No substitution, no reformulation, no line becoming unavailable after payment. The paperwork has read the same way on every one of them, which is the part I would put in front of a new member as the worked example.
Where HYB sells
Shenzhen Hybio Pharmaceutical Co., Ltd. sells from its own storefront. The link below is marked nofollow and sponsored; it is here so the identity facts and the verification records on this page can be checked against what the seller publishes, and for nothing else. This site is paid nothing for it.
Visit HYB at hybiopharmaceutical.com →
Whatever a storefront claims, the lot on the vial has to match the lot on the certificate. That check is yours and nobody else can do it for you.
Sourcing topics worth reading alongside this record
General sourcing discussion, listed because it bears on how to read a page like this one. These topics are not about HYB and nothing in them is a claim about this supplier.
| Topic | Participants | Replies | Views | Activity |
|---|---|---|---|---|
|
What a regulator's shortage notice actually authorises — what changed since
The question in the title: What a regulator's shortage notice actually authorises — what changed since I will give what I have already checked below so nobody repeats it. Asking what a regulator's document…
|
+22 | 26 | 53k | 7mo |
|
Interpreting a result that disagrees with the supplier's certificate
Interpreting a result that disagrees with the supplier's certificate Writing it up because I had to work it out twice and would rather nobody else did. Structured report rather than an opinion, following the…
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+129 | 153 | 7.3k | 5mo |
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Currency conversion and the cost you did not see
Currency conversion and the cost you did not see — setting out what I have, and where I think it stops being reliable. Currency and fees, set out so that the comparison can be checked. Quoted amount,…
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2 | 44k | 2mo | |
|
Documenting a supplier's response to a discrepancy — does this still hold?
Documenting a supplier's response to a discrepancy — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Structured question about turnaround and…
|
+47 | 52 | 58k | 16mo |
|
Aggregate verification data across the directory, with caveats
On the subject in the title: Aggregate verification data across the directory, with caveats Working notes rather than a conclusion. I have spent a fortnight trying to pin aggregate verification data down and…
|
+64 | 74 | 4.6k | 14h |
|
Prescription requirements and telehealth models
Prescription requirements and telehealth models Writing it up because I had to work it out twice and would rather nobody else did. Proposing that prescription requirements and telehealth models deserves a…
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+91 | 97 | 5.4k | 7mo |
Maintenance
Maintainers: KLindqvist, q.zhao_qa. Next review due 8 February 2027.
To add a record, file a structured report in vendor reports with the compound, lot, service, method and result. Reports missing any of those are moved to the discussion rather than the record. Allegations without documentation are hidden under R6 and the hiding is logged.
On what each service's report establishes: Janoshik Analytical · Medutest · PeptideMeter · VendorInvestigate