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Research Methods · Statistics · continued

Correlation in a self-tracked dataset: what it can support posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

YA
y.adebayoTL2 Moderator22 Aug 2024#61

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

3 likes 23mo
MH
ms_hollowayTL4Mass spectrometrist22 Aug 2024#62
policy_reader, post #32: On post #28 — agreed on the reasoning, with one qualification. Relative risk and odds ratios: both compare the rate in one group to the rate in another. Relative risk is easier to understand. Odds ratios are standard in many analyses but can be misinterpreted. Go to post

Picking up post #59: that is the part I would want checked first.

P-values and significance: p<0.05 means the data would be surprising if the null hypothesis were true, not that the null hypothesis is false. A non-significant p-value does not mean "no effect".

0 likes in reply to #32 23mo
MI
m.ibarraTL2 Moderator22 Aug 2024 · edited#63

Regression to the mean: if you select people with extreme values (very high or very low), their next measurement is often less extreme just by chance. This can look like a treatment effect when it is just statistics.

23 likes 23mo
SL
s.leclercTL4 Moderator22 Aug 2024#64

Confounding: a third variable explains an apparent association. In randomised data, randomisation balances confounders. In observational data, confounders can be adjusted for but unknown ones cannot.

11 likes 23mo
CA
c.amankwahTL222 Aug 2024#65
TH
TL4_HalvorsenTL4Leader · Journal club22 Aug 2024#66
owen.brady, post #40: Effect sizes: the magnitude of a difference, not just whether it is statistically significant. A difference that is significant (p Go to post

This follows post #63 rather than contradicting it.

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

1 like in reply to #40 23mo
RE
r.ekstromTL2 Moderator23 Aug 2024#67
NHuddleston, post #26: Picking up post #23: that is the part I would want checked first. Confidence intervals: rather than a single point estimate, a range of plausible values. A narrow interval means precise measurement; a wide interval means measurement is imprecise. Wider intervals (more uncertainty) are honest about limitation. Go to post

Multiplicity and multiple comparisons: if you test many hypotheses, the chance of finding a false positive by random chance increases. That is why pre-specifying the primary hypothesis matters.

31 likes in reply to #26 23mo
EF
endo_fellow_rkTL3Endocrinology fellow23 Aug 2024#68

Confidence intervals: rather than a single point estimate, a range of plausible values. A narrow interval means precise measurement; a wide interval means measurement is imprecise. Wider intervals (more uncertainty) are honest about limitation.

16 likes 23mo
LV
l.vukovicTL2 Moderator23 Aug 2024#69

Absence of evidence and evidence of absence: if a study is small and finds no effect, that is absence of evidence, not evidence of absence. A larger study might find an effect that a small study missed.

10 likes 23mo
SC
s.chowdhuryTL3Regular23 Aug 2024#70

P-values and significance: p<0.05 means the data would be surprising if the null hypothesis were true, not that the null hypothesis is false. A non-significant p-value does not mean "no effect".

3 likes 23mo
JD
j.delacroixTL323 Aug 2024#71
SO
sa.okonkwoTL2 Moderator23 Aug 2024#72

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

0 likes 23mo
AW
a.westergaardTL3Regular23 Aug 2024#73

Number needed to treat: how many people need to be treated to prevent one bad outcome or achieve one good outcome. More intuitive than relative risk reduction.

4 likes 23mo
MM
m.malinowskiTL2 Moderator23 Aug 2024#74
sharps_bin, post #16: Coming back to post #14, because the follow-up matters more than the original answer. Multiplicity and multiple comparisons: if you test many hypotheses, the chance of finding a false positive by random chance increases. That is why pre-specifying the primary hypothesis matters. Go to post

I read post #72 twice before replying, because I had assumed the opposite.

Relative risk and odds ratios: both compare the rate in one group to the rate in another. Relative risk is easier to understand. Odds ratios are standard in many analyses but can be misinterpreted.

12 likes in reply to #16 23mo
ML
m.lindqvistTL2 Moderator23 Aug 2024 · edited#75

Number needed to treat: how many people need to be treated to prevent one bad outcome or achieve one good outcome. More intuitive than relative risk reduction.

19 likes 23mo
RR
r.restrepoTL2 Moderator23 Aug 2024#76

Relative risk and odds ratios: both compare the rate in one group to the rate in another. Relative risk is easier to understand. Odds ratios are standard in many analyses but can be misinterpreted.

0 likes 23mo
CC
c.correiaTL2 Moderator23 Aug 2024#77
n.kuusela, post #8: Power and sample size: a study might be too small to detect a real effect (low power). Sample size calculations help determine how many participants are needed to detect an effect of a given magnitude. Go to post

Picking up post #74: that is the part I would want checked first.

P-values and significance: p<0.05 means the data would be surprising if the null hypothesis were true, not that the null hypothesis is false. A non-significant p-value does not mean "no effect".

2 likes in reply to #8 23mo
ME
me.eriksenTL2 Moderator23 Aug 2024#78
m.guerrero, post #25: Relative risk and odds ratios: both compare the rate in one group to the rate in another. Relative risk is easier to understand. Odds ratios are standard in many analyses but can be misinterpreted. Go to post

Coming back to post #76, because the follow-up matters more than the original answer.

Absence of evidence and evidence of absence: if a study is small and finds no effect, that is absence of evidence, not evidence of absence. A larger study might find an effect that a small study missed.

8 likes in reply to #25 23mo
KS
k.salinasTL2 Moderator23 Aug 2024#79

Confidence intervals: rather than a single point estimate, a range of plausible values. A narrow interval means precise measurement; a wide interval means measurement is imprecise. Wider intervals (more uncertainty) are honest about limitation.

4 likes 23mo
DF
d.fontaineTL223 Aug 2024#80
C
chromatogramTL4Analytical chemist23 Aug 2024#81
m.onwuka, post #39: Power and sample size: a study might be too small to detect a real effect (low power). Sample size calculations help determine how many participants are needed to detect an effect of a given magnitude. Go to post

Worth separating two things that post #77 runs together.

Confounding: a third variable explains an apparent association. In randomised data, randomisation balances confounders. In observational data, confounders can be adjusted for but unknown ones cannot.

2 likes in reply to #39 23mo
MI
m.ibarraTL2 Moderator23 Aug 2024#82
v.malinowski, post #21: I read post #19 twice before replying, because I had assumed the opposite. Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive. Go to post

Regression to the mean: if you select people with extreme values (very high or very low), their next measurement is often less extreme just by chance. This can look like a treatment effect when it is just statistics.

0 likes in reply to #21 23mo
EF
endo_fellow_rkTL3Endocrinology fellow23 Aug 2024#83

Effect sizes: the magnitude of a difference, not just whether it is statistically significant. A difference that is significant (p<0.05) might be too small to matter. A large effect might not be significant if sample size is small.

26 likes 23mo
TD
t.dumitruTL2 Moderator23 Aug 2024 · edited#84

Power and sample size: a study might be too small to detect a real effect (low power). Sample size calculations help determine how many participants are needed to detect an effect of a given magnitude.

13 likes 23mo
CB
c.bakkerTL2 Moderator23 Aug 2024#85
k.okafor, post #49: Relative risk and odds ratios: both compare the rate in one group to the rate in another. Relative risk is easier to understand. Odds ratios are standard in many analyses but can be misinterpreted. Go to post

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

4 likes in reply to #49 23mo
JN
j.nascimentoTL2 Moderator23 Aug 2024#86

Number needed to treat: how many people need to be treated to prevent one bad outcome or achieve one good outcome. More intuitive than relative risk reduction.

0 likes 23mo
SL
s.leclercTL4 Moderator23 Aug 2024#87

Absence of evidence and evidence of absence: if a study is small and finds no effect, that is absence of evidence, not evidence of absence. A larger study might find an effect that a small study missed.

0 likes 23mo
MB
m.brobergTL2 Moderator23 Aug 2024#88

Picking up post #85: that is the part I would want checked first.

P-values and significance: p<0.05 means the data would be surprising if the null hypothesis were true, not that the null hypothesis is false. A non-significant p-value does not mean "no effect".

18 likes 23mo
AF
a.friskTL2 Moderator23 Aug 2024#89
y.adebayo, post #61: Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had been repeating something I had not checked carefully enough. Go to post

Effect sizes: the magnitude of a difference, not just whether it is statistically significant. A difference that is significant (p<0.05) might be too small to matter. A large effect might not be significant if sample size is small.

20 likes in reply to #61 23mo
TN
t.ndiayeTL2 Moderator23 Aug 2024#90

post #89 is right about the mechanism and I think understates the practical bit.

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

9 likes 23mo