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Outcomes · Body composition · continued

DXA precision and the least significant change for lean mass — the long version posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

BV
bias_varianceTL4Biostatistician18 May 2025#61

Maintenance phase: tracking body composition during maintenance (weight stable) is different from tracking during active loss. Changes are smaller and precision becomes more important.

15 likes 14mo
MS
m.steinerTL2 Moderator19 May 2025#62

On post #58 — agreed on the reasoning, with one qualification.

DXA (dual-energy X-ray absorptiometry): the standard for body composition in research. Precision is roughly ±1 kg for lean mass. Two scans six months apart on the same machine with the same technician give you useful information. Two scans six weeks apart on different machines tell you about the machines.

30 likes 14mo
FD
f.demirTL2Regular19 May 2025#63
two_year_line, post #7: post #6 is right about the mechanism and I think understates the practical bit. Precision versus accuracy: the precision you need depends on what question you are answering. "Am I losing fat?" requires less precision than "Is my lean mass preservation within the expected range?" Go to post

Bioelectric impedance analysis: less precise than DXA and strongly affected by hydration state. Not reliable for detecting month-to-month changes. Useful for trend over years if done consistently.

0 likes in reply to #7 14mo
AI
a.iyerTL2 Moderator19 May 2025#64

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

3 likes 14mo
RM
r.mcalisterTL3Regular19 May 2025#65

Precision versus accuracy: the precision you need depends on what question you are answering. "Am I losing fat?" requires less precision than "Is my lean mass preservation within the expected range?"

21 likes 14mo
RN
r.nakamuraTL2 Moderator19 May 2025#66

Lean mass loss during rapid weight reduction: depends on protein intake, resistance training volume, and total energy deficit. Adequate protein and maintaining training intensity both help preserve lean mass.

0 likes 14mo
DT
dexa_twice_yearlyTL3Regular20 May 2025#67
lc_gradient, post #1: On the subject in the title: DXA precision and the least significant change for lean mass — the long version Working notes rather than a conclusion. Maintenance rather than loss, which is the part of this that almost nobody writes about. I have been at roughly the same weight for 9 months. The interesting questions are all different… Go to post

This follows post #64 rather than contradicting it.

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

1 like in reply to #1 14mo
HF
h.friskTL2 Moderator20 May 2025 · edited#68
vial_table, post #16: post #15 is right about the mechanism and I think understates the practical bit. Visceral fat: DXA does not distinguish visceral (organ-associated) fat from subcutaneous fat. That distinction might matter but requires different imaging to measure. Go to post

Maintenance phase: tracking body composition during maintenance (weight stable) is different from tracking during active loss. Changes are smaller and precision becomes more important.

5 likes in reply to #16 14mo
GP
g.pemberton_ukTL3Regional · UK20 May 2025#69

Comparison to published data: the trials reported mean fat and lean mass changes. Individual results vary around that mean. Being above or below average is not a sign of something wrong.

6 likes 14mo
NB
n.boatengTL2 Moderator20 May 2025#70
a.lindqvist, post #47: Comparison to published data: the trials reported mean fat and lean mass changes. Individual results vary around that mean. Being above or below average is not a sign of something wrong. Go to post

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

16 likes in reply to #47 14mo
AP
abstract_peakTL1Member20 May 2025#71

I read post #69 twice before replying, because I had assumed the opposite.

Ultrasound: thickness of subcutaneous fat at specific sites. Less standardised than DXA and operator-dependent. Useful as a supplementary measure but not as a primary method.

9 likes 14mo
BC
b.correiaTL2 Moderator21 May 2025#72
h.frisk, post #68: Maintenance phase: tracking body composition during maintenance (weight stable) is different from tracking during active loss. Changes are smaller and precision becomes more important. Go to post

Visceral fat: DXA does not distinguish visceral (organ-associated) fat from subcutaneous fat. That distinction might matter but requires different imaging to measure.

2 likes in reply to #68 14mo
NR
n.rowntreeTL3Regular21 May 2025#73

Resting metabolic rate: body composition affects metabolic rate. As fat mass decreases and lean mass is maintained, metabolic rate is usually maintained better than with simple weight loss alone.

0 likes 14mo
RB
r.bakkenTL2 Moderator21 May 2025#74

post #73 is right about the mechanism and I think understates the practical bit.

Changes during titration: measuring body composition during active titration is less useful than measuring after dose is stable. Titration causes fluid shifts that confound body composition.

28 likes 14mo
I
IsaksenTL3Regular21 May 2025#75

Coming back to post #73, because the follow-up matters more than the original answer.

Lean mass loss during rapid weight reduction: depends on protein intake, resistance training volume, and total energy deficit. Adequate protein and maintaining training intensity both help preserve lean mass.

14 likes 14mo
TI
t.ibarraTL2 Moderator21 May 2025#76

Picking up post #73: that is the part I would want checked first.

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

5 likes 14mo
TN
t.nardoneTL3Regular22 May 2025#77
j.vandermolen, post #48: Resting metabolic rate: body composition affects metabolic rate. As fat mass decreases and lean mass is maintained, metabolic rate is usually maintained better than with simple weight loss alone. Go to post

Ultrasound: thickness of subcutaneous fat at specific sites. Less standardised than DXA and operator-dependent. Useful as a supplementary measure but not as a primary method.

0 likes in reply to #48 14mo
NA
n.achebeTL222 May 2025#78
LC
l.chevalierTL3Regular22 May 2025#79

Resting metabolic rate: body composition affects metabolic rate. As fat mass decreases and lean mass is maintained, metabolic rate is usually maintained better than with simple weight loss alone.

2 likes 14mo
MA
m.adebayoTL2 Moderator22 May 2025#80

Comparison to published data: the trials reported mean fat and lean mass changes. Individual results vary around that mean. Being above or below average is not a sign of something wrong.

0 likes 14mo
SO
s.ostergaardTL2 Moderator22 May 2025#81

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

5 likes 14mo
BV
bias_varianceTL4Biostatistician23 May 2025#82
lc_gradient, post #1: On the subject in the title: DXA precision and the least significant change for lean mass — the long version Working notes rather than a conclusion. Maintenance rather than loss, which is the part of this that almost nobody writes about. I have been at roughly the same weight for 9 months. The interesting questions are all different… Go to post

Maintenance phase: tracking body composition during maintenance (weight stable) is different from tracking during active loss. Changes are smaller and precision becomes more important.

13 likes in reply to #1 14mo
HD
h.delgadoTL2 Moderator23 May 2025#83
r.vukovic, post #28: Maintenance phase: tracking body composition during maintenance (weight stable) is different from tracking during active loss. Changes are smaller and precision becomes more important. Go to post

post #82 answers the question as asked. The question underneath it is different.

Precision versus accuracy: the precision you need depends on what question you are answering. "Am I losing fat?" requires less precision than "Is my lean mass preservation within the expected range?"

0 likes in reply to #28 14mo
IT
impurity_tableTL3Analytical chemist23 May 2025#84

On post #80 — agreed on the reasoning, with one qualification.

Changes during titration: measuring body composition during active titration is less useful than measuring after dose is stable. Titration causes fluid shifts that confound body composition.

0 likes 14mo
AI
a.iyerTL2 Moderator23 May 2025#85

Visceral fat: DXA does not distinguish visceral (organ-associated) fat from subcutaneous fat. That distinction might matter but requires different imaging to measure.

2 likes 14mo
RM
r.mcalisterTL3Regular23 May 2025#86

I read post #84 twice before replying, because I had assumed the opposite.

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

9 likes 14mo
MS
m.steinerTL2 Moderator24 May 2025#87
p.fontaine, post #38: post #37 is right about the mechanism and I think understates the practical bit. Bioelectric impedance analysis: less precise than DXA and strongly affected by hydration state. Not reliable for detecting month-to-month changes. Useful for trend over years if done consistently. Go to post

post #86 is right about the mechanism and I think understates the practical bit.

DXA (dual-energy X-ray absorptiometry): the standard for body composition in research. Precision is roughly ±1 kg for lean mass. Two scans six months apart on the same machine with the same technician give you useful information. Two scans six weeks apart on different machines tell you about the machines.

27 likes in reply to #38 14mo
FD
f.demirTL2Regular24 May 2025#88

DXA (dual-energy X-ray absorptiometry): the standard for body composition in research. Precision is roughly ±1 kg for lean mass. Two scans six months apart on the same machine with the same technician give you useful information. Two scans six weeks apart on different machines tell you about the machines.

0 likes 14mo
SD
s.dziedzicTL2 Moderator24 May 2025#89

Picking up post #86: that is the part I would want checked first.

Comparison to published data: the trials reported mean fat and lean mass changes. Individual results vary around that mean. Being above or below average is not a sign of something wrong.

13 likes 14mo
SC
so.cardosoTL2 Moderator24 May 2025#90

Coming back to post #88, because the follow-up matters more than the original answer.

Resting metabolic rate: body composition affects metabolic rate. As fat mass decreases and lean mass is maintained, metabolic rate is usually maintained better than with simple weight loss alone.

26 likes 14mo