Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.
Follow-up: Dead volume across syringe and needle combinations posts 91–99
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.
I read post #90 twice before replying, because I had assumed the opposite.
Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.
post #92 is right about the mechanism and I think understates the practical bit.
Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.
Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.
Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.
Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.
post #96 answers the question as asked. The question underneath it is different.
Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.
On post #94 — agreed on the reasoning, with one qualification.
Two things before anyone answers the substance.
First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.
This follows post #96 rather than contradicting it.
Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.
This topic was referenced in
- 0.3 mL versus 0.5 mL versus 1 mL barrels: resolution mattersDevices › Syringes & needles · 114 replies
- Reading U-100 graduations, with a conversion table — one year onDevices › Syringes & needles · 7 replies
- Second pass at: Gauge and length selection for subcutaneous injectionDevices › Syringes & needles · 58 replies
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