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Evidence · Preprints · continued

The "under review" status pill and when a moderator applies it posts 31–60

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

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a.mwangiTL2 Moderator21 Mar 2026#31

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

28 likes 4mo
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cannula_driftTL3Regular22 Mar 2026#32

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

13 likes 4mo
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b.vestergaardTL2 Moderator23 Mar 2026 · edited#33
d.oyelaran, post #12: Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently. Go to post

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

2 likes in reply to #12 4mo
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BGiordanoTL2Member23 Mar 2026#34
o.vogel, post #4: Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound. Go to post

Picking up post #31: that is the part I would want checked first.

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

0 likes in reply to #4 4mo
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b.solbergTL2 Moderator24 Mar 2026#35

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

0 likes 4mo
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m.coelhoTL225 Mar 2026#36
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k.radichTL2 Moderator25 Mar 2026#37

I read post #35 twice before replying, because I had assumed the opposite.

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

5 likes 4mo
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h.mbekiTL2 Moderator26 Mar 2026#38
Woodhouse, post #9: Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished. Go to post

This follows post #35 rather than contradicting it.

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

0 likes in reply to #9 4mo
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a.reyesTL4 Admin26 Mar 2026#39

On post #35 — agreed on the reasoning, with one qualification.

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

14 likes 4mo
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b.oseiTL2 Moderator27 Mar 2026#40

post #39 answers the question as asked. The question underneath it is different.

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

5 likes 4mo
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bias_varianceTL4Biostatistician28 Mar 2026#41

post #40 answers the question as asked. The question underneath it is different.

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

17 likes 4mo
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d.ferreiraTL2 Moderator28 Mar 2026#42
d.oyelaran, post #12: Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently. Go to post

On post #38 — agreed on the reasoning, with one qualification.

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

0 likes in reply to #12 4mo
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batchlogTL3Regular29 Mar 2026#43

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

0 likes 4mo
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c.chowdhuryTL229 Mar 2026#44
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compounding_ruthTL4Pharmacist30 Mar 2026#45

post #44 is right about the mechanism and I think understates the practical bit.

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

24 likes 4mo
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i.norgaardTL2 Moderator30 Mar 2026#46
baseline_drift, post #18: post #17 is right about the mechanism and I think understates the practical bit. What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint. Go to post

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

0 likes in reply to #18 4mo
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impurity_tableTL3Analytical chemist31 Mar 2026#47

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

1 like 4mo
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s.ostergaardTL2 Moderator1 Apr 2026#48

I read post #46 twice before replying, because I had assumed the opposite.

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

7 likes 4mo
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a.thorneTL21 Apr 2026#49
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j.sandvikTL2 Moderator2 Apr 2026#50

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

18 likes 4mo
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a.eriksenTL2 Moderator2 Apr 2026#51

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

31 likes 4mo
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BBramleyTL3Regular3 Apr 2026#52

This follows post #49 rather than contradicting it.

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

15 likes 4mo
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c.serranoTL2 Moderator3 Apr 2026#53

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

6 likes 4mo
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t.nardoneTL3Regular4 Apr 2026#54
KLindqvist, post #14: I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient. Go to post

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

1 like in reply to #14 4mo
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i.amankwahTL2 Moderator5 Apr 2026#55

Coming back to post #53, because the follow-up matters more than the original answer.

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

0 likes 4mo
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j.vandermolenTL35 Apr 2026#56
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b.correiaTL2 Moderator6 Apr 2026#57
BGiordano, post #34: Picking up post #31: that is the part I would want checked first. Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions. Go to post

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

10 likes in reply to #34 4mo
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g.valckenaereTL3Regular6 Apr 2026#58
coldchain_liu, post #21: I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient. Go to post

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

3 likes in reply to #21 4mo
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a.hartmannTL2 Moderator7 Apr 2026#59
batchlog, post #43: How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint. Go to post

I read post #57 twice before replying, because I had assumed the opposite.

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

16 likes in reply to #43 4mo
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excursion_checkTL3Regular7 Apr 2026#60

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

6 likes 4mo