i.broberg

TL2 Moderator · Bari

Contributes reviews on supplier material. Based in Bari.

Joined 9 February 2025 · last posted 4d

97 posts, newest first. Showing up to 150.

Journal club: what we got wrong in an earlier session Replied, post #117 · Evidence › Journal club · 24 Jul 2026 · 16 likes TRIUMPH (ongoing): Retatrutide phase 3. No results yet. Nothing should be attributed to it because it has not finished. When it does, this discussion will return to it.
Revisiting: Protein density versus volume when you cannot eat much Replied, post #85 · Nutrition & Training › Protein & intake · 20 Jul 2026 · 0 likes Protein targets during weight loss: the standard recommendation is 1.6 to 2.2 grams per kilogram of body weight. Individual requirements vary but that range is a…
NHS criteria and how they are applied in practice Replied, post #32 · Regional › UK & Ireland · 17 Jul 2026 · 4 likes Worth separating two things that post #28 runs together. MHRA is the regulator. Licensed incretin analogues are prescription-only medicines. NHS and private prescribing…
Revisiting: What pooling buys you and what it destroys Replied, post #93 · Evidence › Meta-analyses · 16 Jul 2026 · 3 likes When a meta-analysis is unhelpful: if the included studies are heterogeneous in population, intervention, or outcome, pooling them produces a number that represents…
[2026 update] Regional warehouse stock versus direct despatch Replied, post #135 · Sourcing › Logistics · 15 Jul 2026 · 1 like Declaring contents accurately: declaring accurately reduces intervention risk. A declaration of "peptide research chemical, 5 grams" is better than "vitamin" or "other"…
Documenting a supplier's response to a discrepancy Replied, post #38 · Sourcing › Vendor reports · 14 Jul 2026 · 11 likes post #37 answers the question as asked. The question underneath it is different. Blind submission is worth the effort: have someone else relabel the sample so neither…
Risk-of-bias tools and the judgement they conceal — does this still hold? Replied, post #24 · Evidence › Meta-analyses · 9 Jul 2026 · 26 likes Worth separating two things that post #20 runs together. Number needed to treat from a meta-analysis: can be computed from the pooled estimate if the baseline risk is…
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #88 · Evidence › Journal club · 7 Jul 2026 · 22 likes This follows post #85 rather than contradicting it. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still…
What other technical communities get right that we do not Replied, post #6 · Lounge › Off topic · 6 Jul 2026 · 15 likes Worth separating two things that post #2 runs together. Humour: light, relevant humour is welcome. Cruel humour targeting individuals or groups is not.
[2026 update] Area percent versus weight percent: the confusion that causes most arguments Replied, post #67 · Analytics › HPLC & UHPLC · 4 Jul 2026 · 6 likes This is why a purity figure without the underlying chromatogram is weaker evidence than it appears. It is also why two competent laboratories can report different…
Pooling trials with different estimands Replied, post #55 · Evidence › Meta-analyses · 28 Jun 2026 · 30 likes Worth separating two things that post #51 runs together. Inclusion and exclusion criteria: a meta-analysis is only as good as its inclusion criteria. If the criteria…
Does dual agonism explain the effect size, or is it dose? Replied, post #59 · Compounds › Tirzepatide · 25 Jun 2026 · 20 likes SURMOUNT-OSA is notable because it used an objective physiological endpoint, the apnoea-hypopnoea index, rather than a symptom scale. Two parallel trials, with and…
Coming back to: Reconciling a supplier certificate with an independent result Replied, post #18 · Sourcing › Vendor reports · 25 Jun 2026 · 14 likes Dosing and purity: a vial that is 99% pure might contain 80% of its label claim if the other mass is water, counter-ion, and excipient. Purity and content are…
Second pass at: Programming during a large energy deficit Replied, post #42 · Nutrition & Training › Resistance training · 24 Jun 2026 · 0 likes On post #38 — agreed on the reasoning, with one qualification. Post-weight-loss training: once weight loss is complete and energy deficit ends, training can shift to…
An appeal that succeeded, with the letter structure — the long version Replied, post #118 · Access › Insurance & coverage · 18 Jun 2026 · 11 likes Formulary status: the list of covered medications and the tier (how much you pay) they are on. Checking the current formulary before going to a clinic appointment saves…
Why fasting instructions for oral semaglutide are not optional advice Replied, post #44 · Compounds › Oral incretins · 16 Jun 2026 · 0 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
Official shortage notices and what they authorise Replied, post #100 · Access › Shortages · 11 Jun 2026 · 1 like Picking up post #97: that is the part I would want checked first. Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap…
What a simple presence test is genuinely useful for Started this topic · Analytics › Home & field testing · 5 Jun 2026 · 0 likes What a simple presence test is genuinely useful for — that is the question, and I have not found it answered plainly anywhere I have looked. Working through the…
Lean mass preservation: what the evidence supports — does this still hold? Replied, post #89 · Outcomes › Body composition · 5 Jun 2026 · 24 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
What a certificate commits its issuer to — one year on Replied, post #80 · Analytics › COA interpretation · 2 Jun 2026 · 3 likes Counter-ion form is crucial: peptides are isolated as salts, most often trifluoroacetate from reversed-phase purification or acetate after salt exchange. The…
Angle of injection and whether 90 degrees is always right — the long version Replied, post #13 · Practice › Administration · 29 May 2026 · 3 likes Picking up post #10: that is the part I would want checked first. Pinch or no pinch: the decision depends on needle length and on your own anatomy. A longer needle (8…
Coming back to: Lateral-flow and colorimetric approaches: the specificity problem Replied, post #33 · Analytics › Home & field testing · 29 May 2026 · 0 likes Colorimetric tests: colour intensity correlates with concentration, but the relationship is non-linear at extremes and the correlation depends on the exact conditions…
Reflectance and photometric devices: precision in practice — a second dataset Replied, post #34 · Analytics › Home & field testing · 23 May 2026 · 1 like Immunoassay limitations: tests that use antibodies have cross-reactivity limitations. An antibody raised to semaglutide will cross-react to some degree with tirzepatide…
Prescription portability between countries Replied, post #27 · Access › International · 8 May 2026 · 1 like Customs and import outcomes: different routes have different seizure rates. Some countries are stricter on peptide imports than others. History on a route is more…
Common supplements people ask about, assessed one at a time — a second dataset Replied, post #98 · Practice › Interactions · 2 May 2026 · 26 likes Oral medications versus time: if you take an oral medication 30 minutes before semaglutide (which slows gastric emptying), the delayed stomach emptying affects when and…
Request: show the solution author in the topic list — what changed since Replied, post #45 · Meta › Feature requests · 2 May 2026 · 4 likes Tradeoffs: every feature has a cost in maintenance and complexity. Acknowledging tradeoffs shows you have thought through the implications.
What I would want from a home test that does not exist yet — what changed since Replied, post #3 · marked as the solution · Analytics › Home & field testing · 24 Apr 2026 · 13 likes post #2 answers the question as asked. The question underneath it is different. Immunoassay limitations: tests that use antibodies have cross-reactivity limitations. An…
Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Replied, post #2 · Compounds › Semaglutide · 16 Apr 2026 · 1 like Worth separating two things that the opening post runs together. On alcohol: the labelling does not contraindicate it, but it raises gastric irritation risk and…
Bioimpedance and hydration: why the number moves Replied, post #31 · Outcomes › Body composition · 15 Apr 2026 · 0 likes post #30 answers the question as asked. The question underneath it is different. Visceral fat: DXA does not distinguish visceral (organ-associated) fat from…
Moderation log format change Replied, post #44 · Meta › Announcements · 13 Apr 2026 · 3 likes I read post #42 twice before replying, because I had assumed the opposite. Feedback to announcements: if you have feedback on an announced change (not a question, but…
Journal club: is percentage weight change the right endpoint? Replied, post #63 · Evidence › Journal club · 13 Apr 2026 · 27 likes I read post #61 twice before replying, because I had assumed the opposite. SOUL (N Engl J Med 2025): Oral semaglutide cardiovascular outcomes. Extends the…
Coming back to: Why a preprint's supplementary material is often the best part Replied, post #29 · Evidence › Preprints · 12 Apr 2026 · 6 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
Reconstitution volumes that produce round numbers, tabulated Replied, post #81 · Practice › Reconstitution · 2 Apr 2026 · 0 likes Swirling versus inverting versus leaving it alone: the vial can be gently warmed (hands around it) and swirled with a rolling motion. Vigorous shaking introduces air…
CJC-1295 with and without DAC: what the modification does Replied, post #18 · Compounds › Secretagogues & GH axis · 23 Mar 2026 · 3 likes Reading a rodent study on a secretagogue without over-extrapolating: rodent studies can show a mechanism is plausible. They cannot show magnitude of effect in humans or…
Adducts: sodium, potassium, and the peak you did not expect — does this still hold? Replied, post #78 · Analytics › Mass spectrometry · 22 Mar 2026 · 0 likes Calibration matters: a high-resolution instrument out of calibration can report mass with ppm error large enough to be uninformative. Check when the instrument was last…
Manufacturer assistance programmes and their eligibility rules Replied, post #11 · Access › Pricing · 14 Mar 2026 · 11 likes Worth separating two things that post #7 runs together. List prices versus negotiated prices: the price a pharmaceutical company publishes and the price an insurance…
Splitting a weekly dose in two: the pharmacokinetic argument against Replied, post #25 · Practice › Dosing & titration · 12 Mar 2026 · 0 likes How the published trials escalated: they used specific step sizes and intervals. The STEP programme used a particular cadence; the SURPASS and SURMOUNT programmes used…
Second pass at: Identical chromatograms across two different lots Replied, post #45 · Sourcing › Red flags · 5 Mar 2026 · 12 likes Pricing patterns: unusually low prices for what are otherwise consistent with market rates might indicate lower quality, stolen goods, or a scam. Unusually high prices…
Measurement error in home scales, with a worked standard deviation Replied, post #16 · Research Methods › Statistics · 2 Mar 2026 · 1 like Multiplicity and multiple comparisons: if you test many hypotheses, the chance of finding a false positive by random chance increases. That is why pre-specifying the…
A plateau that disappeared when I changed how I measured — the long version Replied, post #12 · Outcomes › Progress reports · 28 Feb 2026 · 3 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
[2026 update] A rising related-substance total over six months: degradation or method… Replied, post #50 · Analytics › Impurities & related substances · 16 Feb 2026 · 0 likes Deletion sequences (incomplete coupling during synthesis): lower in mass by one residue. Chromatographically they usually elute earlier or later depending on the…
Managing an unplanned gap in supply Replied, post #27 · Access › Shortages · 9 Feb 2026 · 0 likes Communication from suppliers: a supplier having supply problems usually communicates them. If a supplier goes silent, that is itself information.
Second pass at: Circumference measurements as a poor man's composition estimate Replied, post #43 · Outcomes › Body composition · 22 Jan 2026 · 23 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
Which panel is worth repeating and which is worth ignoring — a second dataset Replied, post #57 · Clinical › Bloodwork · 22 Jan 2026 · 6 likes Biological variation: the person-to-person variation in a biomarker for a healthy person is larger than most people realize. Comparing your result to the reference…
Journal club: LEADER as the historical anchor Replied, post #24 · Evidence › Journal club · 17 Jan 2026 · 6 likes PIONEER 6 (N Engl J Med 2019): Cardiovascular safety trial for oral semaglutide, not efficacy. Non-inferiority for safety was met. The trial was not designed to…
What a good consultation looks like from the other side Replied, post #10 · Clinical › Prescriber conversations · 16 Jan 2026 · 0 likes Worth separating two things that post #6 runs together. Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did…
Second pass at: Adsorptive losses at low concentration, and why dilute solutions are… Replied, post #11 · Practice › Storage & stability · 3 Jan 2026 · 10 likes Temperature excursions: if a vial sat at room temperature for a time, the question is whether the excursion was long enough to cause damage. Hours at room temperature…
What to include when your question involves a chromatogram Replied, post #2 · Start Here › How to Ask · 25 Dec 2025 · 0 likes Asking a follow-up: new topic or reply in the old one? If the answer depends on the previous post, reply. If it is a question that makes sense without the previous…
Temperature loggers worth the money — the long version Replied, post #92 · Devices › Cold chain · 13 Dec 2025 · 8 likes Light protection: avoid direct sunlight and UV exposure. Amber vials or opaque containers reduce light exposure. For short-term storage, keeping the vial in its…
Reading an interaction checker output critically Replied, post #64 · Practice › Interactions · 12 Dec 2025 · 7 likes I read post #62 twice before replying, because I had assumed the opposite. Sulfonylureas and meglitinides: these agents stimulate insulin release and carry hypoglycemia…
Tirzepatide in type 2 diabetes: the SURPASS programme, summarised honestly — the long… Replied, post #70 · Compounds › Tirzepatide · 10 Dec 2025 · 12 likes The 2.5 mg starting dose is not a therapeutic dose in the sense that weight loss is minimal at that dose. It is a tolerance-testing dose. Confusing the purpose of a…
[2026 update] Storing lyophilised material long term: what governs the shelf life Replied, post #32 · Practice › Storage & stability · 6 Dec 2025 · 0 likes On post #28 — agreed on the reasoning, with one qualification. I want to gently push back on the reply above about storage extrapolation. The advice is sound and the…
Revisiting: Why tirzepatide titration schedules have more steps than semaglutide's Replied, post #80 · Compounds › Tirzepatide · 16 Nov 2025 · 0 likes Coming back to post #78, because the follow-up matters more than the original answer. SURMOUNT-4 used a randomised withdrawal design: everyone titrated, then those on…
Critiquing an observational claim about a class effect — one year on Replied, post #9 · Evidence › Study critique · 14 Nov 2025 · 32 likes Bias towards the null and bias away from the null: different criticisms have different directions. Differential dropout might bias away from null; conservative…
Insomnia at a dose step: reported experiences Replied, post #24 · Wellbeing › Sleep · 12 Nov 2025 · 13 likes Sleep quality versus quantity: some people report changes to sleep duration; others report changes to sleep quality without duration change. Both can matter for…
Airline travel with a temperature-sensitive injectable Replied, post #13 · Devices › Cold chain · 7 Nov 2025 · 3 likes Worth separating two things that post #9 runs together. Reconstituted solutions: once reconstituted, solutions are less stable than lyophilised powder. Refrigerate…
Request: a diff view for wiki revisions — the long version Replied, post #63 · Meta › Feature requests · 31 Oct 2025 · 3 likes post #62 is right about the mechanism and I think understates the practical bit. Use case: explain why you think the feature would help. "I would use this to..." makes…
SURMOUNT-4 and what withdrawal data does and does not tell an individual — one year on Replied, post #62 · Compounds › Tirzepatide · 21 Oct 2025 · 13 likes Mass and charge states: tirzepatide is about 4813.5 Da and on an electrospray instrument you would expect to see charge states mostly in the 2+ to 4+ range, the same as…
Where to report an adverse event officially, by region — a second dataset Replied, post #37 · Safety › Adverse events · 20 Oct 2025 · 12 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
A 40-week log with the measurement method stated Replied, post #26 · Outcomes › Progress reports · 17 Oct 2025 · 0 likes Non-scale victories: muscle gain or maintenance, clothing fit, energy level, and capability (like climbing stairs without breathlessness) are measurements that…
A comparison of home results against a laboratory result on the same vial Replied, post #48 · Analytics › Home & field testing · 12 Oct 2025 · 21 likes I read post #46 twice before replying, because I had assumed the opposite. Immunoassay limitations: tests that use antibodies have cross-reactivity limitations. An…
Availability by country, dated, with primary sources Replied, post #13 · Access › International · 7 Oct 2025 · 0 likes Regulatory position dates: a regulatory position is only current as of when it was written. Rechecking is prudent, especially if you saw it months ago.
How the vendor documentation pages are maintained, and by whom — what changed since Replied, post #68 · Sourcing › Vendor reports · 6 Oct 2025 · 25 likes Structured report format: compound, lot, independent testing service, method as reported, result, and the certificate figure for the same lot. One lot is one lot. It…
Citing a preprint in a maintained document: our rule and its reasoning — does this still… Replied, post #58 · Evidence › Preprints · 30 Sep 2025 · 0 likes Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere.…
Payment method and the leverage it gives you, ranked Replied, post #55 · Sourcing › Payments · 22 Sep 2025 · 23 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
Coming back to: Oxidation and deamidation mass shifts, tabulated Replied, post #38 · Analytics › Mass spectrometry · 22 Sep 2025 · 10 likes Coming back to post #36, because the follow-up matters more than the original answer. Desalting before analysis: some samples need desalting to remove salts that…
Cross-border purchase rules within the EU Replied, post #12 · Regional › European Union · 16 Sep 2025 · 6 likes post #11 is right about the mechanism and I think understates the practical bit. Pharmacy practice: pharmacies in different EU countries differ in conservatism about…
Second pass at: What "verified" means on our vendor pages, stated narrowly Replied, post #14 · Sourcing › Vendor reports · 10 Sep 2025 · 17 likes On post #10 — agreed on the reasoning, with one qualification. Multiple services on one lot: agreement across two independent laboratories is stronger than a high…
Confounding by indication, explained with a concrete example Replied, post #13 · Evidence › Study critique · 1 Sep 2025 · 26 likes Bias towards the null and bias away from the null: different criticisms have different directions. Differential dropout might bias away from null; conservative…
[2026 update] What we do not know about retatrutide, listed explicitly Replied, post #62 · Compounds › Retatrutide · 24 Aug 2025 · 18 likes Coming back to post #60, because the follow-up matters more than the original answer. Retatrutide is investigational. Anything obtained outside a trial is by definition…
[2026 update] Mood changes: monitoring, and when to involve a professional Replied, post #18 · Wellbeing › Mental health · 21 Aug 2025 · 0 likes Identity and self-image: for some people, weight and body size are central to identity. Large change to body size can affect identity. This is not pathological; it is…
Cross-border purchase within the EU: the actual rules Replied, post #3 · marked as the solution · Access › International · 27 Jun 2025 · 8 likes Coming back to the opening post, because the follow-up matters more than the original answer. Customs and import outcomes: different routes have different seizure…
[2026 update] Clearance pathways and what renal impairment changes Replied, post #49 · Pharmacology › Pharmacokinetics · 16 Jun 2025 · 9 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
Second pass at: Semaglutide and alcohol: what is actually documented Replied, post #13 · Compounds › Semaglutide · 13 Jun 2025 · 12 likes The STEP programme populations were selected: enrollment criteria required baseline body mass index over 30, no recent blood pressure crisis, no recent retinopathy, no…
Temperature loggers worth the money — the long version Started this topic · Devices › Cold chain · 10 Jun 2025 · 28 likes On the subject in the title: Temperature loggers worth the money — the long version Working notes rather than a conclusion. Reporting something rather than asking about…
Obstructive sleep apnoea and a hard endpoint in this class Replied, post #86 · Clinical › Comorbidities · 16 May 2025 · 0 likes Obstructive sleep apnoea: SURMOUNT-OSA used an objective endpoint, the apnoea-hypopnoea index. Reduction was substantial. Whether the benefit is weight loss or a direct…
Pages past their review date, listed — does this still hold? Replied, post #27 · Meta › Wiki maintenance · 11 May 2025 · 0 likes post #26 is right about the mechanism and I think understates the practical bit. Outdated external links: if a maintained page links to external sources and those links…
Asking about a compound your prescriber has not heard of Replied, post #31 · Clinical › Prescriber conversations · 4 May 2025 · 0 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
Reading a trial's population section before its results — does this still hold? Replied, post #61 · Evidence › Trials · 2 May 2025 · 17 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
Reading order for a first week here, and what to skip until later Replied, post #75 · Start Here › Welcome · 9 Apr 2025 · 28 likes There is no stupid-questions rule and no penalty for asking badly. The response to a poorly framed question is a request for clarification, not rudeness. That is a…
A 10 mg vial reconstituted three different ways, compared — the long version Replied, post #23 · Practice › Reconstitution · 15 Mar 2025 · 8 likes Arithmetic step by step: a 5 mg vial with 2 mL of diluent gives (5 mg) / (2 mL) = 2.5 mg/mL. On a U-100 syringe at that concentration, 100 units = 1 mL = 2.5 mg, so…
Second pass at: Regression to the mean in progress reports Replied, post #76 · Research Methods › Statistics · 5 Mar 2025 · 0 likes I read post #74 twice before replying, because I had assumed the opposite. Effect sizes: the magnitude of a difference, not just whether it is statistically…
Telehealth prescribing models in the US Replied, post #54 · Regional › North America · 4 Feb 2025 · 7 likes Cross-border purchase: buying in the US and bringing to Canada or vice versa involves both countries' import rules. The medication is legal but crossing borders with it…
What changed in 2026, by region Replied, post #115 · Access › International · 2 Feb 2025 · 16 likes Insurance and coverage: coverage decisions are national. A compound approved in one country might not be covered by insurance in another. Checking both approval and…
Revisiting: What a well-designed human trial of a secretagogue would look like Replied, post #34 · Compounds › Secretagogues & GH axis · 16 Jan 2025 · 0 likes post #33 is right about the mechanism and I think understates the practical bit. GHRH analogues versus ghrelin mimetics are often conflated but they are different…
Follow-up: Oral contraceptives and delayed emptying: what the data shows Replied, post #36 · Practice › Interactions · 13 Jan 2025 · 0 likes On post #32 — agreed on the reasoning, with one qualification. Separation timing versus clinically important interaction: a separation timing inconvenience (taking one…
[2026 update] Journal club: SURPASS-2 and the semaglutide 1 mg comparator Replied, post #90 · Evidence › Journal club · 12 Jan 2025 · 0 likes TRIUMPH (ongoing): Retatrutide phase 3. No results yet. Nothing should be attributed to it because it has not finished. When it does, this discussion will return to it.
Foaming during reconstitution and whether it matters Started this topic · Practice › Reconstitution · 31 Dec 2024 · 7 likes Posting this under the heading it deserves: Foaming during reconstitution and whether it matters Everything below is what sits behind that. I have read the maintained…
What changed in 2026, by region Replied, post #37 · Access › International · 24 Dec 2024 · 0 likes Coming back to post #35, because the follow-up matters more than the original answer. Currency and exchange rates: paying in different currencies has different costs…
Persistent vomiting and the threshold for seeking help — one year on Replied, post #12 · Safety › Adverse events · 19 Dec 2024 · 20 likes Worth separating two things that post #8 runs together. How to document: date, exact symptom or event, severity, duration, outcome, any medical attention sought.…
Request: a diff view for wiki revisions Replied, post #29 · Meta › Feature requests · 7 Dec 2024 · 0 likes Deprecation requests: if you think a feature should be removed or changed, that is also a request. Explain why you think it would improve the site.
Injection-site reactions: describing them precisely enough to be useful Replied, post #2 · Practice › Side effects · 12 Nov 2024 · 0 likes the opening post answers the question as asked. The question underneath it is different. Injection site reaction: local erythema, nodules, or induration at injection…
A page that has drifted out of date and needs a maintainer Replied, post #20 · Documentation › Wiki requests · 20 Oct 2024 · 13 likes Correction requests: if you spot an error in a maintained page, note it here with the specific correction. The maintainer will review and update if justified.
Second pass at: A field-by-field walk through a certificate of analysis Replied, post #65 · Analytics › COA interpretation · 25 Sep 2024 · 17 likes When a document puts the specification in the result column, it has told you the release criterion, not the measurement. Those are different claims and the second is…
Correlation in a self-tracked dataset: what it can support Replied, post #101 · Research Methods › Statistics · 24 Aug 2024 · 18 likes This follows post #98 rather than contradicting it. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still…
How this community labels and discusses unrefereed work Replied, post #117 · Evidence › Preprints · 27 Jul 2024 · 0 likes post #116 answers the question as asked. The question underneath it is different. Discussing preprints in this community: bring them in for early discussion, label them…
Journal club: FLOW and the renal composite, component by component Replied, post #34 · Evidence › Journal club · 12 Jul 2024 · 7 likes post #33 answers the question as asked. The question underneath it is different. SURPASS-2 (N Engl J Med 2021): Direct comparison of tirzepatide with semaglutide 1.0…