[2026 update] Reflux appearing for the first time at a dose step

Posting this under the heading it deserves: Reflux appearing for the first time at a dose step Everything below is what sits behind that.

Reporting something rather than asking about it, in case the pattern is useful to anyone else.

Over 20 weeks I logged this consistently: date, dose, time of day, and a simple severity score from 0 to 4 for each symptom. That is 82 data points, all self-reported, all unblinded, and collected by someone who knew what he expected to find. Treat it accordingly.

The reason I am posting is that my experience does not match the shape people usually describe here, and I would like to know whether that is unusual or whether the usual description is just the loudest version.

On the opening post — agreed on the reasoning, with one qualification.

Vomiting: when it is expected (first-dose reactions or early titration) and when it is a reason to stop and seek help are different. Occasional vomiting during titration is ordinary. Persistent vomiting or vomiting of a new character later in treatment warrants contact with your clinician.

Picking up post #2: that is the part I would want checked first.

Timeline matters: onset, duration, pattern over days or weeks, relationship to injection and to meals all provide information that "I have nausea" does not. Posting those details gets better responses than reporting the symptom alone.