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worked example

Contains arithmetic shown step by step.

139 topics 42 solved Group: Status

Practice 47 Research Methods 26 Start Here 25 Data & Tools 14 Pharmacology 14 Devices 13

Related in this group: solved · open question · needs a source · long read · beginner friendly · data table · disputed

139 topics · page 4 of 5

Topic	Participants	Replies	Views	Activity
Dose numbers across compounds are not on the same scale Practice › Dosing & titration titration worked example tirzepatide missed dose Dose numbers across compounds are not on the same scale — setting out what I have, and where I think it stops being reliable. I have read the maintained page on this and I still have a gap, so I am asking…		2	1.6k	9mo
Follow-up: Why "dose equivalence" between different incretin analogues is a weak concept Practice › Dosing & titration dose reduction worked example tirzepatide missed dose Solved Asking directly, because I could not find a straight answer: Why "dose equivalence" between different incretin analogues is a weak concept Reporting something rather than asking about it, in case the pattern…	+7	11	26k	9mo
Follow-up: Subcutaneous absorption kinetics and site differences Pharmacology › Pharmacokinetics semaglutide liraglutide worked example Subcutaneous absorption kinetics and site differences — setting out what I have, and where I think it stops being reliable. I would like to understand what this number means before I repeat it anywhere. A…		4	9.9k	10mo
Follow-up: Why the titration planner refuses to produce a schedule below a floor Data & Tools › Calculators worked example syringe units site feedback The question in the title: Why the titration planner refuses to produce a schedule below a floor I will give what I have already checked below so nobody repeats it. I would like to understand what this number…	+120	146	14k	10mo
Washout: how long is long enough, and for what purpose Pharmacology › Pharmacokinetics semaglutide missed dose worked example Closed Washout: how long is long enough, and for what purpose — setting out what I have, and where I think it stops being reliable. A documentation question rather than an analytical one. I have a certificate in…	+63	70	13k	10mo
Titles that describe the question, not the situation — what changed since Start Here › How to Ask beginner friendly site feedback worked example guidelines Posting this under the heading it deserves: Titles that describe the question, not the situation — what changed since Everything below is what sits behind that. Question in the title. Context below, and I…	+29	33	29k	10mo
A ten-fold dose error caught before injection Devices › Syringes & needles needle gauge & length worked example syringe units dead volume Closed A ten-fold dose error caught before injection — setting out what I have, and where I think it stops being reliable. Reporting something rather than asking about it, in case the pattern is useful to anyone…	+95	103	26k	10mo
Revisiting: Filter needles: when they help and what they cost you Devices › Syringes & needles worked example needle gauge & length subcutaneous injection dead volume Closed Revisiting: Filter needles: when they help and what they cost you — setting out what I have, and where I think it stops being reliable. A question about technique rather than about dose. I have been doing the…	+48	52	6.6k	11mo
Why most self-reports here are not experiments, and that is fine Research Methods › N-of-1 designs confounding worked example data table effect size Closed Why most self-reports here are not experiments, and that is fine — that is the question, and I have not found it answered plainly anywhere I have looked. I have seen SURPASS-2 ( N Engl J Med , 2021) cited in…		2	46k	11mo
Foaming during reconstitution and whether it matters Practice › Reconstitution concentration maths bacteriostatic water reconstitution syringe units Posting this under the heading it deserves: Foaming during reconstitution and whether it matters Everything below is what sits behind that. I have read the maintained page on this and I still have a gap, so I…	+19	24	466	11mo
Why "add 2 mL" is not an instruction — a second dataset Practice › Reconstitution concentration maths bacteriostatic water worked example dead volume Why "add 2 mL" is not an instruction — a second dataset — that is the question, and I have not found it answered plainly anywhere I have looked. Reporting something rather than asking about it, in case the…		2	13k	11mo
Multiplicity when you track fifteen variables Research Methods › Statistics effect size heterogeneity confounding worked example Solved Multiplicity when you track fifteen variables — setting out what I have, and where I think it stops being reliable. Comparing LEADER ( N Engl J Med , 2016) with SURMOUNT-OSA ( N Engl J Med , 2024) and finding…		2	60k	11mo
Checking someone else's arithmetic: a worked example thread Practice › Reconstitution reconstitution syringe units concentration maths worked example Checking someone else's arithmetic: a worked example thread Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated, because I have seen how…	+74	78	895	11mo
The storage lookup and where its data comes from Data & Tools › Calculators worked example site feedback syringe units concentration maths Solved Closed The storage lookup and where its data comes from — setting out what I have, and where I think it stops being reliable. A documentation question rather than an analytical one. I have a certificate in front of…	+4	8	4.1k	11mo
Subcutaneous absorption kinetics and site differences Pharmacology › Pharmacokinetics missed dose worked example semaglutide Wiki Posting this under the heading it deserves: Subcutaneous absorption kinetics and site differences Everything below is what sits behind that. I would like to understand what this number means before I repeat…	+15	19	3.9k	12mo
Revisiting: What to include when your question involves arithmetic Start Here › How to Ask worked example site feedback onboarding beginner friendly Revisiting: What to include when your question involves arithmetic — setting out what I have, and where I think it stops being reliable. Question in the title. Context below, and I have tried to include the…	+21	25	384	12mo
Regression to the mean in progress reports Research Methods › Statistics number needed to treat heterogeneity confounding effect size On the subject in the title: Regression to the mean in progress reports Working notes rather than a conclusion. Session topic: PIONEER 6 ( N Engl J Med , 2019). Please read it before posting; the discussion…	+30	34	49k	12mo
Titrating on tolerability rather than on the calendar Practice › Dosing & titration dose reduction tirzepatide worked example missed dose On the subject in the title: Titrating on tolerability rather than on the calendar Working notes rather than a conclusion. I have read the maintained page on this and I still have a gap, so I am asking rather…		2	31k	13mo
[2026 update] Clearance pathways and what renal impairment changes Pharmacology › Pharmacokinetics missed dose liraglutide worked example Solved On the subject in the title: Clearance pathways and what renal impairment changes Working notes rather than a conclusion. A documentation question rather than an analytical one. I have a certificate in front…	+63	69	50k	13mo
[2026 update] Dose numbers across compounds are not on the same scale Practice › Dosing & titration dose reduction worked example semaglutide titration On the subject in the title: Dose numbers across compounds are not on the same scale Working notes rather than a conclusion. I have read the maintained page on this and I still have a gap, so I am asking…	+14	18	1.2k	13mo
A 5 mg vial and a 0.25 mg dose: the arithmetic in full — what changed since Practice › Reconstitution dead volume bacteriostatic water reconstitution syringe units Closed Posting this under the heading it deserves: A 5 mg vial and a 0.25 mg dose: the arithmetic in full — what changed since Everything below is what sits behind that. I have read the maintained page on this and I…	+86	93	25k	13mo
Validating a calculator against hand arithmetic — what changed since Data & Tools › Calculators concentration maths site feedback worked example Solved Posting this under the heading it deserves: Validating a calculator against hand arithmetic — what changed since Everything below is what sits behind that. Working through the identity arithmetic and I would…	+121	137	21k	13mo
Albumin binding and how it produces a long half-life Pharmacology › Pharmacokinetics semaglutide liraglutide worked example tirzepatide Albumin binding and how it produces a long half-life — setting out what I have, and where I think it stops being reliable. I would like to understand what this number means before I repeat it anywhere. A…	+38	44	6.6k	14mo
Pre-registering a personal experiment, seriously Research Methods › N-of-1 designs worked example data table effect size confounding Pre-registering a personal experiment, seriously — setting out what I have, and where I think it stops being reliable. Comparing STEP 4 ( JAMA , 2021) with SUSTAIN 6 ( N Engl J Med , 2016) and finding the…	+96	119	58k	14mo
Second pass at: Designing a personal experiment that could change your mind Research Methods › N-of-1 designs worked example effect size confounding data table Solved Second pass at: Designing a personal experiment that could change your mind Writing it up because I had to work it out twice and would rather nobody else did. Session topic: SURPASS-4 ( Lancet , 2021). Please…	+39	44	632	14mo
Reaching a dose and staying there for a year: a longitudinal note Practice › Dosing & titration worked example tirzepatide titration semaglutide Reaching a dose and staying there for a year: a longitudinal note Writing it up because I had to work it out twice and would rather nobody else did. I have read the maintained page on this and I still have a…		2	763	15mo
Second pass at: Gauge and length selection for subcutaneous injection Devices › Syringes & needles subcutaneous injection syringe units worked example needle gauge & length Posting this under the heading it deserves: Second pass at: Gauge and length selection for subcutaneous injection Everything below is what sits behind that. A question about technique rather than about dose.…	+50	58	14k	15mo
Over-dilution: when your dose falls below one readable graduation Practice › Reconstitution concentration maths syringe units bacteriostatic water dead volume On the subject in the title: Over-dilution: when your dose falls below one readable graduation Working notes rather than a conclusion. I have read the maintained page on this and I still have a gap, so I am…	+15	19	248	15mo
Revisiting: Bug report: the reconstitution calculator and a rounding edge case Data & Tools › Calculators worked example site feedback syringe units Revisiting: Bug report: the reconstitution calculator and a rounding edge case — setting out what I have, and where I think it stops being reliable. Working through the identity arithmetic and I would like it…	+109	122	5.8k	17mo
Titrating on tolerability rather than on the calendar — the long version Practice › Dosing & titration worked example missed dose titration tirzepatide Titrating on tolerability rather than on the calendar — the long version Writing it up because I had to work it out twice and would rather nobody else did. Reporting something rather than asking about it, in…		2	7.7k	17mo