Latest topics page 50

Revisiting: How to bring a laboratory report to an appointment usefully — setting out what I have, and where I think it stops being reliable. Asking about bring a laboratory directly, because I have read four…

Blind submission and why it changes minds — setting out what I have, and where I think it stops being reliable. What changes if the standard account of blind submission is wrong? I ask because I have been…

On the subject in the title: Trifluoroacetate content and its consequences Working notes rather than a conclusion. A follow-up question about Trifluoroacetate content that I did not know to ask the first…

Air bubbles in a subcutaneous injection: the honest risk assessment Writing it up because I had to work it out twice and would rather nobody else did. An honest uncertainty about air bubbles rather than a…

On the subject in the title: Journal club: SURPASS-2 and the semaglutide 1 mg comparator Working notes rather than a conclusion. Session topic: SURPASS-2 ( N Engl J Med , 2021). Please read it before posting;…

Progressive overload when the scale is falling — one year on Writing it up because I had to work it out twice and would rather nobody else did. The question about Progressive overload that I actually want…

Second pass at: Hoarding and why it makes a shortage worse Writing it up because I had to work it out twice and would rather nobody else did. Documenting an access outcome, dated, because everything in this…

Posting this under the heading it deserves: Requesting a page: what makes a good request — what changed since Everything below is what sits behind that. What changes if the standard account of Requesting a…

Pen wastage and its effect on real cost Writing it up because I had to work it out twice and would rather nobody else did. Two things I would like separated before anyone answers on pen wastage, because they…

Posting this under the heading it deserves: Tracking a preprint to publication: a worked example — the long version Everything below is what sits behind that. A preprint question rather than a question about…

Prediction intervals and why they are more honest than confidence intervals Writing it up because I had to work it out twice and would rather nobody else did. Prediction intervals — I have the observation and…

Second pass at: Sodium, potassium and magnesium when intake drops Writing it up because I had to work it out twice and would rather nobody else did. A hydration and intake question, with the figures, since…

A site rotation scheme that is easy enough to actually follow Writing it up because I had to work it out twice and would rather nobody else did. A follow-up question about site rotation scheme that I did not…

Type 2 diabetes and the largest part of the evidence base — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Trying to work out what would count…

PIONEER 6 cardiovascular safety, read as a safety trial rather than an efficacy one — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. Posting a…

Posting this under the heading it deserves: Splitting a vial for two laboratories: how to do it without ruining both — what changed since Everything below is what sits behind that. Something about Splitting a…

Revisiting: A staff appointment, and what the role involves — setting out what I have, and where I think it stops being reliable. Reading back through what has been written here about staff appointment, three…

Revisiting: Joined after a search result and stayed Writing it up because I had to work it out twice and would rather nobody else did. Saying hello, and stating my interest so that it is on the record rather…

Posting this under the heading it deserves: Priming a pen and whether the primed volume is wasted — one year on Everything below is what sits behind that. I would like to disagree carefully with the settled…

Why a preprint's supplementary material is often the best part I have a specific reason for asking rather than idle curiosity, and the context is below. A question about how this site should cite something…

On the subject in the title: Deconvolution of a multiply charged envelope Working notes rather than a conclusion. Working through the identity arithmetic and I would like it checked. tirzepatide has a…

Asking directly, because I could not find a straight answer: What consumer-accessible tests can and cannot determine Something about consumer-accessible tests does not reconcile and I would like a second pair…

On the subject in the title: Gradient steepness and apparent purity: a worked comparison Working notes rather than a conclusion. I have spent a fortnight trying to pin gradient steepness and apparent purity…

Posting this under the heading it deserves: Revisiting: A fridge failure and how I assessed the contents afterwards Everything below is what sits behind that. The question about fridge failure that I actually…

On the subject in the title: Reporting a discrepancy without making an allegation Working notes rather than a conclusion. Asking about reporting a discrepancy directly, because I have read four threads on it…

Posting this under the heading it deserves: Hepatic effects of glucagon receptor agonism: the mechanistic worry Everything below is what sits behind that. Something about hepatic effects of glucagon receptor…

The C-cell question: rodent findings and their human context — what changed since — setting out what I have, and where I think it stops being reliable. What changes if the standard account of c-cell question…

Meeting a protein target on a suppressed appetite — one year on — setting out what I have, and where I think it stops being reliable. Asking about Meeting a protein target directly, because I have read four…

On the subject in the title: MHRA statements, read directly — the long version Working notes rather than a conclusion. Asking about MHRA statements directly, because I have read four threads on it and each…

Pen mechanics when the cartridge is nearly empty — setting out what I have, and where I think it stops being reliable. Trying to work out what would count as evidence on pen mechanics, before collecting any.…