Latest topics page 41
Topics ordered by most recent activity across all 71 subcategories.
1,535 topics · page 41 of 52
| Topic | Participants | Replies | Views | Activity |
|---|---|---|---|---|
|
Pregnancy as an absolute contraindication — the long version
On the subject in the title: Pregnancy as an absolute contraindication — the long version Working notes rather than a conclusion. A narrow question about Pregnancy, deliberately narrow, because the broad…
|
2 | 5.3k | 14mo | |
|
A claim built entirely on a subgroup analysis
A claim built entirely on a subgroup analysis Writing it up because I had to work it out twice and would rather nobody else did. I would like to disagree carefully with the settled view on claim built, and I…
|
+71 | 80 | 1.1k | 14mo |
|
Why oral semaglutide needs an absorption enhancer at all — what changed since
Asking directly, because I could not find a straight answer: Why oral semaglutide needs an absorption enhancer at all — what changed since What changes if the standard account of oral semaglutide is wrong? I…
|
2 | 61k | 14mo | |
|
Delayed gastric emptying and oral medication absorption: which drugs matter
On the subject in the title: Delayed gastric emptying and oral medication absorption: which drugs matter Working notes rather than a conclusion. A follow-up question about delayed gastric emptying and oral…
|
+110 | 116 | 43k | 14mo |
|
How to bring a laboratory report to an appointment usefully
How to bring a laboratory report to an appointment usefully — that is the question, and I have not found it answered plainly anywhere I have looked. Asking about bring a laboratory directly, because I have…
|
2 | 41k | 14mo | |
|
Why we hide unevidenced fraud accusations and log the hiding
Why we hide unevidenced fraud accusations and log the hiding — that is the question, and I have not found it answered plainly anywhere I have looked. Filing a documentation observation rather than a result,…
|
+97 | 106 | 63k | 14mo |
|
Albumin binding and how it produces a long half-life
Albumin binding and how it produces a long half-life — setting out what I have, and where I think it stops being reliable. A narrow question about albumin binding, deliberately narrow, because the broad…
|
+38 | 44 | 6.6k | 14mo |
|
An orphaned page with no inbound links
An orphaned page with no inbound links — setting out what I have, and where I think it stops being reliable. What changes if the standard account of orphaned page is wrong? I ask because I have been treating…
|
+44 | 48 | 7.5k | 14mo |
|
Pre-registering a personal experiment, seriously
Pre-registering a personal experiment, seriously — setting out what I have, and where I think it stops being reliable. A narrow question about pre-registering a personal experiment, deliberately narrow,…
|
+96 | 119 | 58k | 14mo |
|
A well-designed study with a badly written abstract
Posting this under the heading it deserves: A well-designed study with a badly written abstract Everything below is what sits behind that. Reading back through what has been written here about well-designed…
|
+117 | 128 | 7.2k | 14mo |
|
Documenting an adverse event properly — the long version
Posting this under the heading it deserves: Documenting an adverse event properly — the long version Everything below is what sits behind that. A narrow question about Documenting an adverse event,…
|
+1 | 5 | 4.8k | 14mo |
|
Cost per milligram, computed honestly across formats — the long version
Cost per milligram, computed honestly across formats — the long version Writing it up because I had to work it out twice and would rather nobody else did. Documenting an access outcome, dated, because…
|
+111 | 124 | 24k | 14mo |
|
Shakes versus food: a pragmatic assessment — the long version
On the subject in the title: Shakes versus food: a pragmatic assessment — the long version Working notes rather than a conclusion. A narrow question about Shakes versus food, deliberately narrow, because the…
|
+36 | 41 | 28k | 14mo |
|
Excipient function in a licensed injectable
Excipient function in a licensed injectable Writing it up because I had to work it out twice and would rather nobody else did. I was wrong about excipient function in a thread last spring and I would like to…
|
+3 | 7 | 36k | 14mo |
|
[2026 update] Building a sensible monitoring schedule with your prescriber
Posting this under the heading it deserves: Building a sensible monitoring schedule with your prescriber Everything below is what sits behind that. Reading back through what has been written here about…
|
+22 | 26 | 5.1k | 14mo |
|
DXA precision and the least significant change for lean mass — the long version
On the subject in the title: DXA precision and the least significant change for lean mass — the long version Working notes rather than a conclusion. A question about measurement precision rather than about…
|
+97 | 111 | 22k | 14mo |
|
HbA1c lag and what it can and cannot tell you at eight weeks
HbA1c lag and what it can and cannot tell you at eight weeks Writing it up because I had to work it out twice and would rather nobody else did. Something about hba1c lag does not reconcile and I would like a…
|
+14 | 18 | 2.6k | 14mo |
|
Reading a trial's population section before its results — does this still hold?
Reading a trial's population section before its results — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Reading STEP 1 ( N Engl J Med , 2021)…
|
+140 | 154 | 5.4k | 14mo |
|
Requesting a translation of an existing page
Requesting a translation of an existing page — setting out what I have, and where I think it stops being reliable. Requesting a translation keeps being re-asked here and I think that is because the answer is…
|
+16 | 20 | 7.1k | 14mo |
|
Domestic fridge temperature mapping: a cheap experiment
Domestic fridge temperature mapping: a cheap experiment Writing it up because I had to work it out twice and would rather nobody else did. Collecting what is known about domestic fridge temperature mapping in…
|
2 | 182 | 14mo | |
|
Second pass at: Obstructive sleep apnoea and a hard endpoint in this class
Second pass at: Obstructive sleep apnoea and a hard endpoint in this class — setting out what I have, and where I think it stops being reliable. Something about Obstructive sleep apnoea does not reconcile and…
|
2 | 726 | 14mo | |
|
UK access routes, dated and sourced — a second dataset
Posting this under the heading it deserves: UK access routes, dated and sourced — a second dataset Everything below is what sits behind that. Regional question, dated January 2026, because everything in this…
|
+76 | 82 | 25k | 14mo |
|
Follow-up: Is "synergy" the right word for the combination data?
Is "synergy" the right word for the combination data? I have a specific reason for asking rather than idle curiosity, and the context is below. Putting the numbers in the first post, because a question about…
|
2 | 41k | 14mo | |
|
One lot is one lot: when a report becomes a pattern
Posting this under the heading it deserves: One lot is one lot: when a report becomes a pattern Everything below is what sits behind that. Structured report rather than an opinion, following the format the…
|
2 | 19k | 14mo | |
|
What SELECT changed about how semaglutide is discussed, and what it did not
Asking directly, because I could not find a straight answer: What SELECT changed about how semaglutide is discussed, and what it did not I was wrong about SELECT in a thread last spring and I would like to…
|
+120 | 132 | 2k | 14mo |
|
Coverage for the indication versus for the drug
Coverage for the indication versus for the drug — setting out what I have, and where I think it stops being reliable. The question about coverage that I actually want answered is the second one below. The…
|
+70 | 79 | 18k | 14mo |
|
Follow-up: Tesamorelin has an approved indication — what that changes about the evidence
Posting this under the heading it deserves: Tesamorelin has an approved indication — what that changes about the evidence Everything below is what sits behind that. What changes if the standard account of…
|
+63 | 68 | 18k | 14mo |
|
Telehealth prescribing models in the US
Telehealth prescribing models in the US Writing it up because I had to work it out twice and would rather nobody else did. Trying to work out what would count as evidence on telehealth prescribing models,…
|
+95 | 102 | 6.1k | 14mo |
|
When to stop reading forums, including this one — the long version
Asking directly, because I could not find a straight answer: When to stop reading forums, including this one — the long version Something that has come up for me and that I suspect is more common than the…
|
+23 | 27 | 8.3k | 14mo |
|
Talking to a therapist about this specifically — does this still hold?
The question in the title: Talking to a therapist about this specifically — does this still hold? I will give what I have already checked below so nobody repeats it. A question about the part of this that…
|
+59 | 65 | 13k | 14mo |