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1,535 topics · page 35 of 40

Topic	Participants	Replies	Views	Activity
Why "any advice?" is the least effective ending for a post — the long version Start Here › How to Ask guidelines site feedback worked example onboarding Solved Asking directly, because I could not find a straight answer: Why "any advice?" is the least effective ending for a post — the long version Counting it rather than describing it, because the count is the part…	+77	83	1.6k	9mo
Semaglutide versus liraglutide head to head: reading STEP 8 carefully Compounds › Semaglutide STEP programme SELECT trial randomised trial type 2 diabetes Under review On the subject in the title: Semaglutide versus liraglutide head to head: reading STEP 8 carefully Working notes rather than a conclusion. I would like to disagree carefully with the settled view on…	+72	81	1.5k	9mo
Pages past their review date, listed — does this still hold? Meta › Wiki maintenance review date moderation citation check maintainership Solved Closed Pages past their review date, listed — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. I would like to disagree carefully with the settled view…	+26	31	52k	15mo
DXA precision and the least significant change for lean mass — the long version Outcomes › Body composition bioimpedance lean mass loss data table On the subject in the title: DXA precision and the least significant change for lean mass — the long version Working notes rather than a conclusion. A question about measurement precision rather than about…	+97	111	22k	14mo
Coming back to: Official shortage notices and what they authorise Access › Shortages FDA compounding shortage formulary Official shortage notices and what they authorise Writing it up because I had to work it out twice and would rather nobody else did. Official shortage notices — I have the observation and I do not trust my…	+85	92	5.5k	11mo
Lean mass preservation: what the evidence supports Outcomes › Body composition lean mass loss bioimpedance DXA Lean mass preservation: what the evidence supports Writing it up because I had to work it out twice and would rather nobody else did. Trying to work out what would count as evidence on lean mass preservation,…	+23	27	347	14mo
Cost per milligram, computed honestly across formats — a second dataset Access › Pricing cost per milligram formulary compounding Closed Cost per milligram, computed honestly across formats — a second dataset Writing it up because I had to work it out twice and would rather nobody else did. Documenting an access outcome, dated, because…		2	27k	13mo
Criticising the method without criticising the authors — one year on Evidence › Study critique confounding effect size disputed risk of bias Solved Closed On the subject in the title: Criticising the method without criticising the authors — one year on Working notes rather than a conclusion. A methods question rather than a substantive one, about Criticising…	+16	20	61k	11mo
Why "add 2 mL" is not an instruction — a second dataset Practice › Reconstitution concentration maths bacteriostatic water worked example dead volume Why "add 2 mL" is not an instruction — a second dataset — that is the question, and I have not found it answered plainly anywhere I have looked. I have read the maintained page on this and I still have a gap,…		2	13k	11mo
Subcutaneous absorption kinetics and site differences Pharmacology › Pharmacokinetics missed dose worked example semaglutide Wiki Posting this under the heading it deserves: Subcutaneous absorption kinetics and site differences Everything below is what sits behind that. Asking about subcutaneous absorption kinetics and site directly,…	+15	19	3.9k	12mo
Lyophilisation and why the cake looks the way it does Pharmacology › Formulation chemistry sterile water bacteriostatic water storage cloudy or discoloured solution Posting this under the heading it deserves: Lyophilisation and why the cake looks the way it does Everything below is what sits behind that. I was wrong about lyophilisation in a thread last spring and I…	+33	37	60k	6mo
Realistic expectations for strength while losing weight quickly — does this still hold? Nutrition & Training › Resistance training DXA fatigue lean mass loss Solved Realistic expectations for strength while losing weight quickly — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Working notes on Realistic…		2	11k	10mo
Specificity, linearity, accuracy, precision, range, robustness — with real criteria — a second dataset Analytics › Method validation linearity LOD & LOQ recovery Closed On the subject in the title: Specificity, linearity, accuracy, precision, range, robustness — with real criteria — a second dataset Working notes rather than a conclusion. Posting a small dataset on…	+53	58	7.5k	6mo
Appeal templates and why they are deliberately unemotional Access › Insurance & coverage formulary insurance prior authorisation appeals Posting this under the heading it deserves: Appeal templates and why they are deliberately unemotional Everything below is what sits behind that. A narrow question about appeal templates, deliberately narrow,…	+25	29	764	7mo
IGF-1 as a surrogate endpoint and its limitations — the long version Compounds › Secretagogues & GH axis CJC-1295 observational data ipamorelin needs a source Solved Closed On the subject in the title: IGF-1 as a surrogate endpoint and its limitations — the long version Working notes rather than a conclusion. A narrow question about IGF-1, deliberately narrow, because the broad…	+14	18	53k	12mo
Comparing my trajectory with the trial curves, carefully Outcomes › Progress reports DXA effect size long read data table Solved Posting this under the heading it deserves: Comparing my trajectory with the trial curves, carefully Everything below is what sits behind that. Maintenance rather than loss, which is the part of this that…	+86	92	54k	7mo
When to stop reading forums, including this one — the long version Wellbeing › Mental health disordered eating beginner friendly mood Solved Asking directly, because I could not find a straight answer: When to stop reading forums, including this one — the long version Something that has come up for me and that I suspect is more common than the…	+23	27	8.3k	14mo
A checklist for reading a certificate in under two minutes — does this still hold? Analytics › COA interpretation documentation quality certificate of analysis amino acid analysis batch & lot numbers Solved A checklist for reading a certificate in under two minutes — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. I would like to understand what this…	+49	55	15k	9mo
TB-500 and thymosin beta-4: the fragment versus the protein Compounds › Repair & healing peptides observational data TB-500 BPC-157 preprint TB-500 and thymosin beta-4: the fragment versus the protein Writing it up because I had to work it out twice and would rather nobody else did. TB-500 and thymosin beta-4: what I expected, what I found, and…	+107	118	22k	11mo
[2026 update] Splitting an overlong document into two Documentation › Wiki requests maintainership review date wiki post promoted to docs Solved Closed Splitting an overlong document into two — setting out what I have, and where I think it stops being reliable. Collecting what is known about Splitting an overlong document in one place, because it is…	+44	48	7k	9mo
Follow-up: History of disordered eating and why it changes the conversation Clinical › Special populations bariatric surgery history older adults pregnancy & planning chronic kidney disease Posting this under the heading it deserves: History of disordered eating and why it changes the conversation Everything below is what sits behind that. What changes if the standard account of History of…	+75	81	23k	10mo
How Janoshik, Medutest, PeptideMeter and VendorInvestigate differ Sourcing › Independent verification blind sampling PeptideMeter Medutest third-party testing How Janoshik, Medutest, PeptideMeter and VendorInvestigate differ I have a specific reason for asking rather than idle curiosity, and the context is below. A question about how a record should be read rather…	+117	130	3.3k	14mo
Reverting an edit that had no revision note Meta › Wiki maintenance citation check moderation review date maintainership Posting this under the heading it deserves: Reverting an edit that had no revision note Everything below is what sits behind that. Reverting an edit: setting out the arithmetic in full, because I have had to…	+17	21	4.5k	12mo
A claim built entirely on a subgroup analysis Evidence › Study critique risk of bias observational data confounding disputed Solved A claim built entirely on a subgroup analysis Writing it up because I had to work it out twice and would rather nobody else did. I would like to disagree carefully with the settled view on claim built, and I…	+71	80	1.1k	14mo
Dizziness on standing: the ordinary explanation first Nutrition & Training › Hydration & electrolytes blood pressure heart rate fatigue Posting this under the heading it deserves: Dizziness on standing: the ordinary explanation first Everything below is what sits behind that. A hydration and intake question, with the figures, since this one…	+22	26	27k	15mo
Titles that describe the question, not the situation Start Here › How to Ask onboarding site feedback guidelines worked example Closed Titles that describe the question, not the situation — setting out what I have, and where I think it stops being reliable. A narrow question about titles, deliberately narrow, because the broad version has…	+137	153	22k	8mo
Temperature logging at home: what is worth the effort Practice › Storage & stability storage beyond-use date cloudy or discoloured solution temperature excursion Temperature logging at home: what is worth the effort — setting out what I have, and where I think it stops being reliable. An honest uncertainty about temperature logging rather than a disguised assertion. I…		2	6.3k	7mo
Hello from a laboratory that does not do peptides Lounge › Introductions onboarding beginner friendly Hello from a laboratory that does not do peptides — setting out what I have, and where I think it stops being reliable. Saying hello, and stating my interest so that it is on the record rather than inferred.…	+2	6	10k	15mo
EU-wide position versus national implementation Regional › European Union EMA personal import cost per milligram formulary Solved Under review EU-wide position versus national implementation Writing it up because I had to work it out twice and would rather nobody else did. Eu-wide position versus national implementation: what I expected, what I…	+22	29	356	11mo
Documenting an adverse event properly — the long version Safety › Adverse events delayed gastric emptying pancreatitis hypoglycaemia gallbladder Posting this under the heading it deserves: Documenting an adverse event properly — the long version Everything below is what sits behind that. A narrow question about Documenting an adverse event,…	+1	5	4.8k	14mo